Labaran dabbobi: Ci gaban ci gaba a Avian Bincike

Labaran 01

Gano na farko na H4N6 subtyme na cutar mura a cikin Mallard ducks (Anas platyrhynchos (Anas platyrhynchos) a cikin Isra'ila

Avishai Lublin, Nikki Shkoda, Irina Shkoda, Ronina Shkoda, Rono Sila

PMID: 35687561; Doi: 10.1111 / tbed.14610

Kwayar cutar Avian (AIV) tana haifar da babbar barazana ga dabba da lafiyar ɗan adam a duk duniya. Kamar yadda Waterfowl ke watsa AIV a duk duniya, bincika yawan ɗaukar Aiv yana da mahimmanci don fahimtar watsawar cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtuka da mutane. A cikin wannan binciken, H4N6 Substypepe aiV da aka ware don farko daga samfuran Faelecal na daji ducks (Anas platyrthynchos) a cikin Isra'ila. Sakamako na Phylogenetic na ha da kwayoyin halitta sun nuna cewa wannan iri yana da alaƙa da ƙasashen Asiya da Asiya. Kamar yadda Isra'ila take tare da hanya ta Arctic-Africa ta Afirka, ana tsammanin cewa zurin ya gabatar da tsuntsayen da tsuntsaye masu ƙaura. Binciken Phylogenetic na halittar al'adu (PB1, PB2, PB2, NS, mai alaƙa na Phylogenetic wanda ya faru a wannan ware. Wannan h4N6 subtype na AIV yana da babban adadin aladu, yana iya cutar da cutar lafiya a gaba.

Labaran 02

Takaitaccen bayanin cutar Avian a cikin EU, Maris-Yuni 2022

Hukumar Kula da Tsarin Abincin Turai ta Turai, Cibiyar Turai don rigakafin cuta da keli, Labaran Hukumomin Tarayyar Turai don mura

PMID: 35949938; PMCID: PMC9356771; Doi: 10.2903 / j.efsa.022.7415

A cikin 2021-2022, sosai pathogenic avian muraenza (HPAI) shine mafi muni a Turai, tare da wadanda suka ta'allaka 2,398 a Turai da ke haifar da tsuntsaye miliyan 36 da suka haifar da gurasa. Tsakanin 16 Maris da 10 Yuni 2022, jimillar kasashe 28 na EU / Eea) sun ware daga kaji (410 lokuta) da tsuntsayen daji (22 ga lokuta). A lokacin da ake bita, kashi 86% na fashewar kiwon kaji sun kasance saboda watsa HPAIV, tare da lissafin kaji na ci gaba da kashi 6% kuma sauran kasashen da abin ya shafa kasa da 2% kowannensu. Jamus tana da mafi yawan barkewar fashewa a cikin tsuntsayen daji (158 lokuta na Netherlands (98 Hears) da UK (48 hali).

Sakamakon nazarin kwayoyin halitta sun nuna cewa a halin yanzu Npar ta kasance a yanzu a cikin Turai akasari ne 2.3.4 b. Tun daga rahoton karshe, H5n6, H9n2 H3n2 da aka bayar da rahoton kamuwa da H3N8 biyu da kuma H5N1 na kamuwa da H5N1 a cikin Amurka. An tantance haɗarin kamuwa da cuta kamar ƙasa gabaɗaya da low zuwa matsakaici don yawan jama'a a EU / EEA.

 Labaran 03

Mutations a cikin ragowar 127, 183 da 212 a kan totar Ha shafi

Antigeniciity, kwayar halitta da patogenicity na H9n2 Avian mura cutar virus

Mnglu fan,Bing Liang,Yongzhen Zhao,Kuping zhang,Qingzheng Liu,Miao Tian,Yiqing zheng,Huizhi xia,Yasuo Suzuki,Hualan Chen,Muhiu ping

PMID: 347243434343434343434343434343434343434343411 / tbed.14363

Kwayar cutar H9N2 na cutar Avian (AIV) tana daya daga cikin manyan magungunan da ke shafar lafiyar masana'antar kaji. A cikin wannan binciken, juzu'i biyu na H9N2 Substype AV tare da irin asalin halittar amma a / Chicken / Jiangsu / 76 / Jianguwa (JSiangsu / 76 / Jianguwa (JSIstan / 76 / Jianguwa (JSIstan / 76/18 Bincike na jerin JS / 75 da JS / 76 sun banbanta a cikin rago uku (127, 183 da 212) na Hemuglutinin (ha). Binciken bambance-bambance a cikin kaddarorin na halittu tsakanin JS / 75 da JS / 77, shida na Ezerto Rico / 8/1934 (pr834 (pr834 (pr834) a matsayin babban sarkar. Bayanai daga gwajin kai na kaji da Gwaje-gwaje na hi sun nuna cewa R-76 / PR8 sun nuna mafi ambaton ambaton Antigenic a matsayi 12 acid acid 127 da 183 a cikin gene na Gene. CIGABA da hankali ya tabbatar da cewa Glyconyation a shafin 127N ne ya faru a JS / 76 da mutuwarsa. Receptor da ke daure 'yansayen da suka nuna cewa duk karfin ƙwayoyin cuta ne, in banda hadayar da ke da karancin iskar mawuyacin karar. Kinetics girma da linzamin kwamfuta sun nuna cewa cutar 127 ga glycosy da aka sake rubutawa a cikin sel na 1279 kuma ba shi da kwayar cutar ta daji. Don haka, GlycoSyLation da maye gurbi na Amino suna da alhakin bambance-bambance da cututtukan ƙwayar 22 na H9n2.

Source: Cibiyar Kiwon Lafiya ta China