Marasa lafiyar huhu, shin gwajin MRD ya zama dole?

MRD (Ƙananan Cuta), ko Ƙananan Rago Cuta, ƙananan ƙwayoyin cutar kansa ne (kwayoyin ciwon daji waɗanda ba sa amsawa ko kuma masu juriya ga magani) waɗanda ke cikin jiki bayan maganin ciwon daji.
Ana iya amfani da MRD azaman alamar halitta, tare da sakamako mai kyau wanda ke nufin cewa ragowar raunuka za a iya gano su bayan maganin ciwon daji (ana samun ƙwayoyin ciwon daji, kuma ragowar ƙwayoyin cutar kansa na iya zama masu aiki kuma su fara ninka bayan maganin ciwon daji, wanda zai haifar da sake dawowa na ciwon daji). cuta), yayin da mummunan sakamako yana nufin cewa ba a gano ragowar raunuka ba bayan maganin ciwon daji (ba a sami kwayoyin cutar kansa ba);
Sanannen abu ne cewa gwajin MRD yana taka muhimmiyar rawa wajen gano majinyata marasa lafiya marasa kanana a farkon matakin cutar kansa (NSCLC) da ke cikin haɗarin sake dawowa da kuma jagorantar maganin adjuvant bayan tiyata mai tsauri.
Hanyoyin da za a iya amfani da MRD a ciki:

Don ciwon daji na huhu a farkon matakin aiki

1. Bayan farfadowa mai tsattsauran ra'ayi na farkon matakan marasa lafiya marasa lafiya na huhu, MRD positivity yana nuna babban haɗarin sake dawowa kuma yana buƙatar kulawa ta kusa. Ana ba da shawarar saka idanu na MRD kowane watanni 3-6;
2. Ana ba da shawarar gudanar da gwaje-gwaje na asibiti na asibiti na ciwon huhu mara ƙananan ƙwayar cuta bisa MRD, da kuma samar da daidaitattun zaɓuɓɓukan magani kamar yadda zai yiwu;
3. Ya ba da shawarar bincika rawar MRD a cikin nau'ikan marasa lafiya biyu, ƙwaƙƙwaran ƙirar direba da kuma mummunan halin direba, daban.

Don ciwon huhu mara ƙanƙanta a cikin gida

An ba da shawarar gwajin 1.MRD ga marasa lafiya a cikin cikakkiyar gafara bayan radical chemoradiotherapy don ciwon daji na huhu na gida wanda ba ƙananan ƙananan ƙwayoyin cuta ba, wanda zai iya taimakawa wajen ƙayyade tsinkaye da kuma tsara ƙarin hanyoyin magani;
2. Gwajin gwaji na asibiti na tushen haɗin gwiwa na tushen MRD bayan chemoradiotherapy ana ba da shawarar don samar da ingantaccen zaɓuɓɓukan haɓakar haɓakawa gwargwadon yiwuwa.
Don ci gaban ciwon huhu mara ƙanƙanta
1. Akwai rashin nazarin da ya dace a kan MRD a cikin ci gaban ciwon huhu mara ƙananan ƙwayoyin cuta;
2. An ba da shawarar cewa a gano MRD a cikin marasa lafiya a cikin cikakkiyar gafara bayan tsarin tsarin jiyya don ci gaba da ciwon huhu na huhu wanda ba shi da ƙananan ƙwayoyin cuta, wanda zai iya taimakawa wajen yin hukunci da tsinkaye da kuma samar da ƙarin hanyoyin warkewa;
3. An ba da shawarar yin bincike game da dabarun jiyya na tushen MRD a cikin marasa lafiya a cikin cikakkiyar gafara don tsawaita tsawon lokacin cikakkiyar gafara kamar yadda zai yiwu don marasa lafiya su iya haɓaka amfanin su.

Ana iya ganin cewa saboda rashin binciken da ya dace game da gano MRD a cikin ci gaban ciwon huhu na huhu, ba a bayyana aikace-aikacen gano MRD ba a cikin maganin ciwon daji na huhu na huhu.
A cikin 'yan shekarun nan, ci gaban da aka yi niyya da immunotherapy sun canza yanayin jiyya ga marasa lafiya tare da ci gaba na NSCLC.
Shaidu masu tasowa sun nuna cewa wasu marasa lafiya suna samun rayuwa na dogon lokaci kuma ana tsammanin za su sami cikakkiyar gafara ta hanyar hoto. Sabili da haka, a ƙarƙashin yanayin cewa wasu ƙungiyoyin marasa lafiya tare da ci gaba na NSCLC sun fahimci manufar rayuwa na dogon lokaci, lura da sake dawowar cututtuka ya zama babban batun asibiti, kuma ko gwajin MRD zai iya taka muhimmiyar rawa a ciki ya cancanci a bincika. a cikin ƙarin gwaji na asibiti.